Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue

A fundamental property of infectious agents is their particulate nature: infectivity arises from independently-acting particles rather than as a result of collective action. Assemblies of the protein tau can exhibit seeding behaviour, potentially underlying the apparent spread of tau aggregation in...

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Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Miller, Lauren V. C., Mukadam, Aamir S., Durrant, Claire S., Vaysburd, Marina J., Katsinelos, Taxiarchis, Tuck, Benjamin J., Sanford, Sophie, Sheppard, Olivia, Knox, Claire, Cheng, Shi, James, Leo C., Coleman, Michael P., McEwan, William A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953780/
https://ncbi.nlm.nih.gov/pubmed/33712082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01141-6
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