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Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection

Intestinal barrier leakage constitutes a potential therapeutic target for many inflammatory diseases and represents a disease progression marker during chronic viral infections. However, the causes of altered gut barrier remain mostly unknown. Using murine infection with lymphocytic choriomeningitis...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Labarta-Bajo, Lara, Nilsen, Steven P., Humphrey, Gregory, Schwartz, Tara, Sanders, Karenina, Swafford, Austin, Knight, Rob, Turner, Jerrold R., Zúñiga, Elina I.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953738/
https://ncbi.nlm.nih.gov/pubmed/32880630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192276
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