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Tau antibody isotype induces differential effects following passive immunisation of tau transgenic mice
One of the main pathological hallmarks of Alzheimer’s disease (AD) is the intraneuronal accumulation of hyperphosphorylated tau. Passive immunotherapy is a promising strategy for the treatment of AD and there are currently a number of tau-specific monoclonal antibodies in clinical trials. A proposed...
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| Publié dans: | Acta Neuropathol Commun |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7953551/ https://ncbi.nlm.nih.gov/pubmed/33712083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01147-0 |
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