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Tau physiology and pathomechanisms in frontotemporal lobar degeneration

Frontotemporal lobar degeneration (FTLD) has been associated with toxic intracellular aggregates of hyperphosphorylated tau (FTLD‐tau). Moreover, genetic studies identified mutations in the MAPT gene encoding tau in familial cases of the disease. In this review, we cover a range of aspects of tau fu...

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Dades bibliogràfiques
Publicat a:J Neurochem
Autors principals: Bodea, Liviu‐Gabriel, Eckert, Anne, Ittner, Lars Matthias, Piguet, Olivier, Götz, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094566/
https://ncbi.nlm.nih.gov/pubmed/27306859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13600
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