Structural basis of cytoplasmic Na(V)1.5 and Na(V)1.4 regulation

Voltage-gated sodium channels (Na(V)s) are membrane proteins responsible for the rapid upstroke of the action potential in excitable cells. There are nine human voltage-sensitive Na(V)1 isoforms that, in addition to their sequence differences, differ in tissue distribution and specific function. Thi...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Nathan, Sara, Gabelli, Sandra B., Yoder, Jesse B., Srinivasan, Lakshmi, Aldrich, Richard W., Tomaselli, Gordon F., Ben-Johny, Manu, Amzel, L. Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953540/
https://ncbi.nlm.nih.gov/pubmed/33306788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.202012722
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