Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy

Hypoxia presents a two-fold challenge in the treatment of cancer, as low oxygen conditions induce biological changes that make malignant tissues simultaneously more aggressive and less susceptible to standard chemotherapy. This paper reports the first metal-based photosensitizer that approaches the...

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Bibliografiska uppgifter
I publikationen:Chem Sci
Huvudupphovsmän: Roque, John A., Barrett, Patrick C., Cole, Houston D., Lifshits, Liubov M., Shi, Ge, Monro, Susan, von Dohlen, David, Kim, Susy, Russo, Nino, Deep, Gagan, Cameron, Colin G., Alberto, Marta E., McFarland, Sherri A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Royal Society of Chemistry 2020
Ämnen:
Chemistry
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953430/
https://ncbi.nlm.nih.gov/pubmed/33738085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03008b
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