Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy

Hypoxia presents a two-fold challenge in the treatment of cancer, as low oxygen conditions induce biological changes that make malignant tissues simultaneously more aggressive and less susceptible to standard chemotherapy. This paper reports the first metal-based photosensitizer that approaches the...

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Publicat a:Chem Sci
Autors principals: Roque, John A., Barrett, Patrick C., Cole, Houston D., Lifshits, Liubov M., Shi, Ge, Monro, Susan, von Dohlen, David, Kim, Susy, Russo, Nino, Deep, Gagan, Cameron, Colin G., Alberto, Marta E., McFarland, Sherri A.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2020
Matèries:
Chemistry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953430/
https://ncbi.nlm.nih.gov/pubmed/33738085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03008b
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