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Validation and Optimization of Host Immunological Bio-Signatures for a Point-of-Care Test for TB Disease

The development of a non-sputum-based, point-of-care diagnostic test for tuberculosis (TB) is a priority in the global effort to combat this disease, particularly in resource-constrained settings. Previous studies have identified host biomarker signatures which showed potential, but there is a need...

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Publicado en:Front Immunol
Autores principales: Mutavhatsindi, Hygon, van der Spuy, Gian D., Malherbe, Stephanus T., Sutherland, Jayne S., Geluk, Annemieke, Mayanja-Kizza, Harriet, Crampin, Amelia C., Kassa, Desta, Howe, Rawleigh, Mihret, Adane, Sheehama, Jacob A., Nepolo, Emmanuel, Günther, Gunar, Dockrell, Hazel M., Corstjens, Paul L. A. M., Stanley, Kim, Walzl, Gerhard, Chegou, Novel N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952865/
https://ncbi.nlm.nih.gov/pubmed/33717089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.607827
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