Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis

We investigated host-derived biomarkers that were previously identified in QuantiFERON supernatants, in a large pan-African study. We recruited individuals presenting with symptoms of pulmonary TB at seven peripheral healthcare facilities in six African countries, prior to assessment for TB disease....

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Publicado en:Sci Rep
Autores principales: Chegou, Novel N., Sutherland, Jayne S., Namuganga, Anna-Ritah, Corstjens, Paul LAM, Geluk, Annemieke, Gebremichael, Gebremedhin, Mendy, Joseph, Malherbe, Stephanus, Stanley, Kim, van der Spuy, Gian D., Kriel, Magdalena, Loxton, Andre G., Kriel, Belinda, Simukonda, Felanji, Bekele, Yonas, Sheehama, Jacob A., Nelongo, Josefina, van der Vyver, Marieta, Gebrexabher, Atsbeha, Hailu, Habteyes, Esterhuyse, Maria M., Rosenkrands, Ida, Aagard, Claus, Kidd, Martin, Kassa, Desta, Mihret, Adane, Howe, Rawleigh, Cliff, Jacqueline M., Crampin, Amelia C., Mayanja-Kizza, Harriet, Kaufmann, Stefan H. E., Dockrell, Hazel M., Ottenhoff, Tom H. M., Walzl, Gerhard
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805775/
https://ncbi.nlm.nih.gov/pubmed/29422548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20855-7
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