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Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis

We investigated host-derived biomarkers that were previously identified in QuantiFERON supernatants, in a large pan-African study. We recruited individuals presenting with symptoms of pulmonary TB at seven peripheral healthcare facilities in six African countries, prior to assessment for TB disease....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chegou, Novel N., Sutherland, Jayne S., Namuganga, Anna-Ritah, Corstjens, Paul LAM, Geluk, Annemieke, Gebremichael, Gebremedhin, Mendy, Joseph, Malherbe, Stephanus, Stanley, Kim, van der Spuy, Gian D., Kriel, Magdalena, Loxton, Andre G., Kriel, Belinda, Simukonda, Felanji, Bekele, Yonas, Sheehama, Jacob A., Nelongo, Josefina, van der Vyver, Marieta, Gebrexabher, Atsbeha, Hailu, Habteyes, Esterhuyse, Maria M., Rosenkrands, Ida, Aagard, Claus, Kidd, Martin, Kassa, Desta, Mihret, Adane, Howe, Rawleigh, Cliff, Jacqueline M., Crampin, Amelia C., Mayanja-Kizza, Harriet, Kaufmann, Stefan H. E., Dockrell, Hazel M., Ottenhoff, Tom H. M., Walzl, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805775/
https://ncbi.nlm.nih.gov/pubmed/29422548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20855-7
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