Proteasome 26S subunit, non-ATPases 1 (PSMD1) and 3 (PSMD3), play an oncogenic role in chronic myeloid leukemia by stabilizing nuclear factor-kappa B

Tyrosine kinase inhibitors (TKIs) targeting BCR-ABL1 have revolutionized therapy for chronic myeloid leukemia (CML), paving the way for clinical development in other diseases. Despite success, targeting leukemic stem cells and overcoming drug resistance remain challenges for curative cancer therapy....

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Bibliografski detalji
Izdano u:Oncogene
Glavni autori: Bencomo-Alvarez, Alfonso E., Rubio, Andres J., Olivas, Idaly M., Gonzalez, Mayra A., Ellwood, Rebecca, Fiol, Carme Ripoll, Eide, Christopher A., Lara, Joshua J., Barreto-Vargas, Christian, Jave-Suarez, Luis F., Nteliopoulos, Georgios, Reid, Alistair G., Milojkovic, Dragana, Druker, Brian J., Apperley, Jane, Khorashad, Jamshid S., Eiring, Anna M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952820/
https://ncbi.nlm.nih.gov/pubmed/33712704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01732-6
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