MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis

Alterations to cell polarization or to intercellular junctions are often associated with epithelial cancer progression, including breast cancers (BCa). We show here that the loss of the junctional scaffold protein MAGI1 is associated with bad prognosis in luminal BCa, and promotes tumorigenesis. E-c...

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Udgivet i:Sci Rep
Main Authors: Kantar, Diala, Mur, Emilie Bousquet, Mancini, Maicol, Slaninova, Vera, Salah, Yezza Ben, Costa, Luca, Forest, Elodie, Lassus, Patrice, Géminard, Charles, Boissière-Michot, Florence, Orsetti, Béatrice, Theillet, Charles, Colinge, Jacques, Benistant, Christine, Maraver, Antonio, Heron-Milhavet, Lisa, Djiane, Alexandre
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952706/
https://ncbi.nlm.nih.gov/pubmed/33707576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85056-1
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