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Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders

Accumulation of the protein α-synuclein into insoluble intracellular deposits termed Lewy bodies (LBs) is the characteristic neuropathological feature of LB diseases, such as Parkinson’s disease (PD), Parkinson’s disease dementia (PDD) and dementia with LB (DLB). α-Synuclein aggregation is thought t...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol
Main Authors: Erskine, Daniel, Koss, David, Korolchuk, Viktor I., Outeiro, Tiago F., Attems, Johannes, McKeith, Ian
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952289/
https://ncbi.nlm.nih.gov/pubmed/33515275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-021-02266-7
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