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Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders

Accumulation of the protein α-synuclein into insoluble intracellular deposits termed Lewy bodies (LBs) is the characteristic neuropathological feature of LB diseases, such as Parkinson’s disease (PD), Parkinson’s disease dementia (PDD) and dementia with LB (DLB). α-Synuclein aggregation is thought t...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Erskine, Daniel, Koss, David, Korolchuk, Viktor I., Outeiro, Tiago F., Attems, Johannes, McKeith, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952289/
https://ncbi.nlm.nih.gov/pubmed/33515275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-021-02266-7
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