Activation of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with amines and amino acids

We report the first activation study of the β-class carbonic anhydrase (CA, EC 4.2.1.1) encoded in the genome of the protozoan pathogen Trichomonas vaginalis, TvaCA1. Among 24 amino acid and amine activators investigated, derivatives incorporating a second carboxylic moiety, such as L-Asp, L- and D-...

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Publicado en:J Enzyme Inhib Med Chem
Autores principales: Angeli, Andrea, Urbański, Linda J., Hytönen, Vesa P., Parkkila, Seppo, Supuran, Claudiu T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2021
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Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952076/
https://ncbi.nlm.nih.gov/pubmed/33715570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1897802
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