Inhibition of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with sulphonamides

Sulphonamides and their isosteres are classical inhibitors of the carbonic anhydrase (CAs, EC 4.2.1.1) metalloenzymes. The protozoan pathogen Trichomonas vaginalis encodes two such enzymes belonging to the β-class, TvaCA1 and TvaCA2. Here we report the first sulphonamide inhibition study of TvaCA1,...

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Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Urbański, Linda J., Angeli, Andrea, Hytönen, Vesa P., Di Fiore, Anna, De Simone, Giuseppina, Parkkila, Seppo, Supuran, Claudiu T.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782162/
https://ncbi.nlm.nih.gov/pubmed/33356653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1863958
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