The extracellular loop of the membrane permease VraG interacts with GraS to sense cationic antimicrobial peptides in Staphylococcus aureus

Host defense proteins (HDPs), aka defensins, are a key part of the innate immune system that functions by inserting into the bacterial membranes to form pores to kill invading and colonizing microorganisms. To ensure survival, microorganism such as S. aureus has developed survival strategies to sens...

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Udgivet i:PLoS Pathog
Main Authors: Cho, Junho, Costa, Stephen K., Wierzbicki, Rachel M., Rigby, William F. C., Cheung, Ambrose L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951975/
https://ncbi.nlm.nih.gov/pubmed/33647048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009338
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