Site-Specific Mutation of the Sensor Kinase GraS in Staphylococcus aureus Alters the Adaptive Response to Distinct Cationic Antimicrobial Peptides

The Staphylococcus aureus two-component regulatory system, GraRS, is involved in resistance to killing by distinct host defense cationic antimicrobial peptides (HD-CAPs). It is believed to regulate downstream target genes such as mprF and dltABCD to modify the S. aureus surface charge. However, the...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Cheung, Ambrose L., Bayer, Arnold S., Yeaman, Michael R., Xiong, Yan Q., Waring, Alan J., Memmi, Guido, Donegan, Niles, Chaili, Siyang, Yang, Soo-Jin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249274/
https://ncbi.nlm.nih.gov/pubmed/25287929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02480-14
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