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Success of prophylactic antiviral therapy for SARS-CoV-2: Predicted critical efficacies and impact of different drug-specific mechanisms of action

Repurposed drugs that are safe and immediately available constitute a first line of defense against new viral infections. Despite limited antiviral activity against SARS-CoV-2, several drugs are being tested as medication or as prophylaxis to prevent infection. Using a stochastic model of early phas...

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Podrobná bibliografie
Vydáno v:PLoS Comput Biol
Hlavní autoři: Czuppon, Peter, Débarre, Florence, Gonçalves, Antonio, Tenaillon, Olivier, Perelson, Alan S., Guedj, Jérémie, Blanquart, François
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951973/
https://ncbi.nlm.nih.gov/pubmed/33647008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008752
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