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Cholesterol activates BK channels by increasing KCNMB1 protein levels in the plasmalemma
Calcium-/voltage-gated, large-conductance potassium channels (BKs) control critical physiological processes, including smooth muscle contraction. Numerous observations concur that elevated membrane cholesterol (CLR) inhibits the activity of homomeric BKs consisting of channel-forming alpha subunits....
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7950327/ https://ncbi.nlm.nih.gov/pubmed/33556372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100381 |
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