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Cholesterol antagonism of alcohol inhibition of smooth muscle BK channel requires cell integrity and involves a protein kinase C-dependent mechanism(s)

Alcohol constricts cerebral arteries via inhibition of voltage/calcium-gated, large conductance potassium (BK) channels in vascular myocytes. Using a rat model of high-cholesterol (high-CLR) diet and CLR enrichment of cerebral arteries in vitro, we recently showed that CLR protected against alcohol-...

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Bibliografski detalji
Izdano u:Biochim Biophys Acta Mol Cell Biol Lipids
Glavni autori: Bukiya, Anna N., Dopico, Alex M.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870541/
https://ncbi.nlm.nih.gov/pubmed/33383194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2020.158874
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