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Cross-linking and modification of fibronectin by peroxynitrous acid: Mapping and quantification of damage provides a new model for domain interactions

Fibronectin (FN) is an abundant glycoprotein found in plasma and the extracellular matrix (ECM). It is present at high concentrations at sites of tissue damage, where it is exposed to oxidants generated by activated leukocytes, including peroxynitrous acid (ONOOH) formed from nitric oxide (from indu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mariotti, Michele, Rogowska-Wrzesinska, Adelina, Hägglund, Per, Davies, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7950325/
https://ncbi.nlm.nih.gov/pubmed/33539924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100360
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