Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway

The Notch1-mediated inflammatory response participates in the development of abdominal aortic aneurysm (AAA). The vascular endogenous bioactive peptide intermedin (IMD) plays an important role in maintaining vascular homeostasis. However, whether IMD inhibits AAA by inhibiting Notch1-mediated inflam...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Ni, Xian-Qiang, Zhang, Ya-Rong, Jia, Li-Xin, Lu, Wei-Wei, Zhu, Qing, Ren, Jin-Ling, Chen, Yao, Zhang, Lin-Shuang, Liu, Xin, Yu, Yan-Rong, Jia, Mo-Zhi, Ning, Zhong-Ping, Du, Jie, Tang, Chao-Shu, Qi, Yong-Fen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7950288/
https://ncbi.nlm.nih.gov/pubmed/33535178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202436
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