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A short deletion in the DNA-binding domain of STAT3 suppresses growth and progression of colon cancer cells
In this study, we investigated the effect of a short deletion in the DNA-binding domain of STAT3 (STAT3(del)) on the transcriptional activation of STAT3 target genes and its relationship with colon carcinogenesis. We used the CRISPR-CAS9 gene editing system to delete a short sequence encoding amino...
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| Publicado no: | Aging (Albany NY) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7950243/ https://ncbi.nlm.nih.gov/pubmed/33535185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202439 |
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