Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.

The Stat (signal transducer and activator of transcription) factors transmit cytokine, growth factor, and hormone responses. Seven members of the Stat gene family are known. MGF-Stat5a has been discovered as a mediator of the prolactin response in mammary epithelial cells. Two closely related varian...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Moriggl, R, Gouilleux-Gruart, V, Jähne, R, Berchtold, S, Gartmann, C, Liu, X, Hennighausen, L, Sotiropoulos, A, Groner, B, Gouilleux, F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231569/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.10.5691
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