Interspecies Differences in Proteome Turnover Kinetics Are Correlated With Life Spans and Energetic Demands

Cells continually degrade and replace damaged proteins. However, the high energetic demand of protein turnover generates reactive oxygen species that compromise the long-term health of the proteome. Thus, the relationship between aging, protein turnover, and energetic demand remains unclear. Here, w...

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Bibliografiske detaljer
Udgivet i:Mol Cell Proteomics
Main Authors: Swovick, Kyle, Firsanov, Denis, Welle, Kevin A., Hryhorenko, Jennifer R., Wise, John P., George, Craig, Sformo, Todd L., Seluanov, Andrei, Gorbunova, Vera, Ghaemmaghami, Sina
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7950207/
https://ncbi.nlm.nih.gov/pubmed/33639418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002301
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