Interspecies Differences in Proteome Turnover Kinetics Are Correlated With Life Spans and Energetic Demands

Cells continually degrade and replace damaged proteins. However, the high energetic demand of protein turnover generates reactive oxygen species that compromise the long-term health of the proteome. Thus, the relationship between aging, protein turnover, and energetic demand remains unclear. Here, w...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Swovick, Kyle, Firsanov, Denis, Welle, Kevin A., Hryhorenko, Jennifer R., Wise, John P., George, Craig, Sformo, Todd L., Seluanov, Andrei, Gorbunova, Vera, Ghaemmaghami, Sina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7950207/
https://ncbi.nlm.nih.gov/pubmed/33639418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002301
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