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Thermal Proteome Profiling in Zebrafish Reveals Effects of Napabucasin on Retinoic Acid Metabolism
Thermal proteome profiling (TPP) allows for the unbiased detection of drug–target protein engagements in vivo. Traditionally, 1 cell type is used for TPP studies, with the risk of missing important differentially expressed target proteins. The use of whole organisms would circumvent this problem. Ze...
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| Publié dans: | Mol Cell Proteomics |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7950114/ https://ncbi.nlm.nih.gov/pubmed/33594990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002273 |
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