CXCR6 deficiency impairs cancer vaccine efficacy and CD8(+) resident memory T-cell recruitment in head and neck and lung tumors

BACKGROUND: Resident memory T lymphocytes (T(RM)) are located in tissues and play an important role in immunosurveillance against tumors. The presence of T(RM) prior to treatment or their induction is associated to the response to anti-Programmed cell death protein 1 (PD-1)/Programmed death-ligand 1...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Karaki, Soumaya, Blanc, Charlotte, Tran, Thi, Galy-Fauroux, Isabelle, Mougel, Alice, Dransart, Estelle, Anson, Marie, Tanchot, Corinne, Paolini, Lea, Gruel, Nadege, Gibault, Laure, Lepimpec-Barhes, Francoise, Fabre, Elizabeth, Benhamouda, Nadine, Badoual, Cecile, Damotte, Diane, Donnadieu, Emmanuel, Kobold, Sebastian, Mami-Chouaib, Fathia, Golub, Rachel, Johannes, Ludger, Tartour, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949477/
https://ncbi.nlm.nih.gov/pubmed/33692218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001948
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