NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP)

C-terminal binding proteins (CtBPs) are cotranscriptional factors that play key roles in cell fate. We have previously shown that NAD(H) promotes the assembly of similar tetramers from either human CtBP1 and CtBP2 and that CtBP2 tetramer destabilizing mutants are defective for oncogenic activity. To...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Nichols, Jeffry C., Schiffer, Celia A., Royer, William E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949142/
https://ncbi.nlm.nih.gov/pubmed/33524397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100351
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