Synaptophysin controls synaptobrevin-II retrieval via a cryptic C-terminal interaction site

The accurate retrieval of synaptic vesicle (SV) proteins during endocytosis is essential for the maintenance of neurotransmission. Synaptophysin (Syp) and synaptobrevin-II (SybII) are the most abundant proteins on SVs. Neurons lacking Syp display defects in the activity-dependent retrieval of SybII...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Harper, Callista B., Blumrich, Eva-Maria, Cousin, Michael A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2021
Pynciau:
Accelerated Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948965/
https://ncbi.nlm.nih.gov/pubmed/33769286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100266
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