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Altered synaptobrevin-II trafficking in neurons expressing a synaptophysin mutation associated with a severe neurodevelopmental disorder

Following exocytosis, synaptic vesicles (SVs) have to be reformed with the correct complement of proteins in the correct stoichiometry to ensure continued neurotransmission. Synaptophysin is a highly abundant, integral SV protein necessary for the efficient retrieval of the SV SNARE protein, synapto...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Harper, Callista B., Mancini, Grazia M.S., van Slegtenhorst, Marjon, Cousin, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673032/
https://ncbi.nlm.nih.gov/pubmed/28887151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.08.021
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