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Runx1 regulates zebrafish neutrophil maturation via synergistic interaction with c-Myb

Neutrophils play an essential role in the innate immune defense system in vertebrates. During hematopoiesis, the full function of neutrophils involves maturation of granules and related enzymes. Yet, transcription regulators that promote neutrophil maturation remain largely undefined. Here, two hema...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Huang, Zhibin, Chen, Kemin, Chi, Yali, Jin, Hao, Li, Li, Zhang, Wenqing, Xu, Jin, Zhang, Yiyue
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948814/
https://ncbi.nlm.nih.gov/pubmed/33434583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100272
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