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Loss of runx1 function results in B cell immunodeficiency but not T cell in adult zebrafish
Transcription factor RUNX1 holds an integral role in multiple-lineage haematopoiesis and is implicated as a cofactor in V(D)J rearrangements during lymphocyte development. Runx1 deficiencies resulted in immaturity and reduction of lymphocytes in mice. In this study, we found that runx1(W84X/W84X) mu...
में बचाया:
| में प्रकाशित: | Open Biol |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The Royal Society
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6070721/ https://ncbi.nlm.nih.gov/pubmed/30045885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.180043 |
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