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Region 4 of the RNA polymerase σ subunit counteracts pausing during initial transcription

All cellular genetic information is transcribed into RNA by multisubunit RNA polymerases (RNAPs). The basal transcription initiation factors of cellular RNAPs stimulate the initial RNA synthesis via poorly understood mechanisms. Here, we explored the mechanism employed by the bacterial factor σ in p...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Brodolin, Konstantin, Morichaud, Zakia
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948647/
https://ncbi.nlm.nih.gov/pubmed/33380428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.016299
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