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Ferroptosis drives photoreceptor degeneration in mice with defects in all-trans-retinal clearance
The death of photoreceptor cells in dry age-related macular degeneration (AMD) and autosomal recessive Stargardt disease (STGD1) is closely associated with disruption in all-trans-retinal (atRAL) clearance in neural retina. In this study, we reveal that the overload of atRAL leads to photoreceptor d...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948481/ https://ncbi.nlm.nih.gov/pubmed/33334878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015779 |
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