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Activation of JNK signaling promotes all-trans-retinal–induced photoreceptor apoptosis in mice
Disrupted clearance of all-trans-retinal (atRAL), a component of the visual (retinoid) cycle in the retina, may cause photoreceptor atrophy in autosomal recessive Stargardt disease (STGD1) and dry age-related macular degeneration (AMD). However, the mechanisms underlying atRAL-induced photoreceptor...
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| Foilsithe in: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Biochemistry and Molecular Biology
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7242700/ https://ncbi.nlm.nih.gov/pubmed/32265302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013189 |
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