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Activation of JNK signaling promotes all-trans-retinal–induced photoreceptor apoptosis in mice

Disrupted clearance of all-trans-retinal (atRAL), a component of the visual (retinoid) cycle in the retina, may cause photoreceptor atrophy in autosomal recessive Stargardt disease (STGD1) and dry age-related macular degeneration (AMD). However, the mechanisms underlying atRAL-induced photoreceptor...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Liao, Chunyan, Cai, Binxiang, Feng, Yufeng, Chen, Jingmeng, Wu, Yiping, Zhuang, Jingbin, Liu, Zuguo, Wu, Yalin
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242700/
https://ncbi.nlm.nih.gov/pubmed/32265302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013189
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