Enzymatic and structural properties of human glutamine:fructose-6-phosphate amidotransferase 2 (hGFAT2)

Glycoconjugates play a central role in several cellular processes, and alteration in their composition is associated with numerous human pathologies. Substrates for cellular glycosylation are synthesized in the hexosamine biosynthetic pathway, which is controlled by the glutamine:fructose-6-phosphat...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Oliveira, Isadora A., Allonso, Diego, Fernandes, Tácio V.A., Lucena, Daniela M.S., Ventura, Gustavo T., Dias, Wagner Barbosa, Mohana-Borges, Ronaldo S., Pascutti, Pedro G., Todeschini, Adriane R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948480/
https://ncbi.nlm.nih.gov/pubmed/33303629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015189
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