CCR3 deficiency is associated with increased osteoclast activity and reduced cortical bone volume in adult male mice

Increasing evidence emphasizes the importance of chemokines and chemokine receptors as regulators of bone remodeling. The C–C chemokine receptor 3 (CCR3) is dramatically upregulated during osteoclastogenesis, but the role of CCR3 in osteoclast formation and bone remodeling in adult mice is unknown....

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Rosendahl, Sara, Sulniute, Rima, Eklund, Michaela, Koskinen Holm, Cecilia, Johansson, Marcus J.O., Kindstedt, Elin, Lindquist, Susanne, Lundberg, Pernilla
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948475/
https://ncbi.nlm.nih.gov/pubmed/33303631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015571
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