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Physicochemical Profiling and Comparison of Research Antiplasmodials and Advanced Stage Antimalarials with Oral Drugs

[Image: see text] To understand the property space of antimalarials, we collated a large dataset of research antiplasmodial (RAP) molecules with known in vitro potencies and advanced stage antimalarials (ASAMs) with established oral bioavailability. While RAP molecules are “non-druglike”, ASAM molec...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Bhanot, Amritansh, Sundriyal, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948433/
https://ncbi.nlm.nih.gov/pubmed/33718733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c00104
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