Učitavanje...
Molecular mechanism of selective substrate engagement and inhibitor disengagement of cysteine synthase
O-acetyl serine sulfhydrylase (OASS), referred to as cysteine synthase (CS), synthesizes cysteine from O-acetyl serine (OAS) and sulfur in bacteria and plants. The inherent challenge for CS is to overcome 4 to 6 log-folds stronger affinity for its natural inhibitor, serine acetyltransferase (SAT), a...
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| Izdano u: | J Biol Chem |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7948407/ https://ncbi.nlm.nih.gov/pubmed/33162395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014490 |
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