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Small-molecule control of neurotransmitter sulfonation

Controlling unmodified serotonin levels in brain synapses is a primary objective when treating major depressive disorder—a disease that afflicts ∼20% of the world’s population. Roughly 60% of patients respond poorly to first-line treatments and thus new therapeutic strategies are sought. To this end...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cook, Ian, Cacace, Mary, Wang, Ting, Darrah, Kristie, Deiters, Alexander, Leyh, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948405/
https://ncbi.nlm.nih.gov/pubmed/33485192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015177
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