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Deletion of bone marrow myeloperoxidase attenuates chronic kidney disease accelerated atherosclerosis

Increased myeloperoxidase (MPO) expression and activity are associated with atherosclerotic disease in patients with chronic kidney disease (CKD). However, the causal relationship between MPO and the development and progression of atherosclerosis in patients with CKD is unknown. Eight-week-old male...

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Pubblicato in:J Biol Chem
Autori principali: Mathew, Anna V., Zeng, Lixia, Atkins, Kevin B., Sadri, Kiana N., Byun, Jaeman, Fujiwara, Hideaki, Reddy, Pavan, Pennathur, Subramaniam
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948401/
https://ncbi.nlm.nih.gov/pubmed/33234591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014095
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