Deletion of bone marrow myeloperoxidase attenuates chronic kidney disease accelerated atherosclerosis

Increased myeloperoxidase (MPO) expression and activity are associated with atherosclerotic disease in patients with chronic kidney disease (CKD). However, the causal relationship between MPO and the development and progression of atherosclerosis in patients with CKD is unknown. Eight-week-old male...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Mathew, Anna V., Zeng, Lixia, Atkins, Kevin B., Sadri, Kiana N., Byun, Jaeman, Fujiwara, Hideaki, Reddy, Pavan, Pennathur, Subramaniam
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948401/
https://ncbi.nlm.nih.gov/pubmed/33234591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014095
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