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Total Synthesis and Conformational Analysis of Naturally Occurring Lipovelutibols along with Lead Optimization of Lipovelutibol D

[Image: see text] Four lipopeptaibols, namely, lipovelutibols A–D, were recently isolated from psychrotrophic fungus Trichoderma velutinum and reported to have significant cytotoxic activity against HL-60, MDA-MD-231, A549, and LS180 cancer cell lines. In the present study, these peptides were synth...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Singh, Varun Pratap, Pathania, Anup Singh, Sharma, Sonia, Malik, Fayaz Ahmed, Kumar, Anil, Singh, Deepika, Vishwakarma, Ram A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948224/
https://ncbi.nlm.nih.gov/pubmed/33718698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c04038
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