Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium

OBJECTIVE: The epithelial layer of the GI tract is equipped with innate immune receptors to sense invading pathogens. Dysregulation in innate immune signalling pathways is associated with severe inflammatory diseases, but the responsiveness of GI epithelial cells to bacterial stimulation remains unc...

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Dades bibliogràfiques
Publicat a:Gut
Autors principals: Kayisoglu, Ozge, Weiss, Franziska, Niklas, Carolin, Pierotti, Isabella, Pompaiah, Malvika, Wallaschek, Nina, Germer, Christoph-Thomas, Wiegering, Armin, Bartfeld, Sina
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2021
Matèries:
Gut Microbiota
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948175/
https://ncbi.nlm.nih.gov/pubmed/32571970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-319919
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