Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium

OBJECTIVE: The epithelial layer of the GI tract is equipped with innate immune receptors to sense invading pathogens. Dysregulation in innate immune signalling pathways is associated with severe inflammatory diseases, but the responsiveness of GI epithelial cells to bacterial stimulation remains unc...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Kayisoglu, Ozge, Weiss, Franziska, Niklas, Carolin, Pierotti, Isabella, Pompaiah, Malvika, Wallaschek, Nina, Germer, Christoph-Thomas, Wiegering, Armin, Bartfeld, Sina
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Gut Microbiota
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948175/
https://ncbi.nlm.nih.gov/pubmed/32571970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-319919
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