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Chemical carcinogen-induced rat mammary carcinogenesis is a potential model of p21-activated kinase positive female breast cancer

The p21-activated kinase 1 (PAK1) gene encodes a serine/threonine kinase that is overexpressed in a subset of human breast carcinomas with poor prognosis. The laboratory rat (Rattus norvegicus) orthologous gene is located at Mammary carcinoma susceptibility 3 (Mcs3) QTL on rat chromosome 1. We used...

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Bibliographische Detailangaben
Veröffentlicht in:Physiol Genomics
Hauptverfasser: Duderstadt, Emily L., McQuaide, Sarah A., Sanders, Mary A., Samuelson, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948085/
https://ncbi.nlm.nih.gov/pubmed/33346690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00112.2020
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