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Deletion of the RGD motif in LON-2/glypican is associated with morphological abnormalities

The lon-2 gene in Caenorhabditis elegans encodes a heparan sulfate proteoglycan family glypican that negatively regulates the BMP signaling pathway responsible for controlling body length. LON-2 contains multiple functional domains, including an RGD (Arg-Gly-Asp) motif at amino acid number from 348...

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Foilsithe in:MicroPubl Biol
Main Authors: Park, Aileen, Qiu, Zhongqiang, Lee, Myeongwoo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Caltech Library 2021
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948029/
https://ncbi.nlm.nih.gov/pubmed/33718824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17912/micropub.biology.000376
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