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A Comprehensive Analysis and Splicing Characterization of Naturally Occurring Synonymous Variants in the ATP7B Gene

Next-generation sequencing is effective for the molecular diagnosis of genetic diseases. However, the identification of the clinical significance of synonymous variants remains a challenge. Our previous study showed that some synonymous variants in ATP7B gene produced splicing disruptions, leading t...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Zhou, Xiaoying, Zhou, Wei, Wang, Chunli, Wang, Lan, Jin, Yu, Jia, Zhanjun, Liu, Zhifeng, Zheng, Bixia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947925/
https://ncbi.nlm.nih.gov/pubmed/33719328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.592611
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