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A narrative review of proteolytic targeting chimeras (PROTACs): future perspective for prostate cancer therapy

Proteolysis-TArgeting Chimeras (PROTACs) technology, as a strategy to chemically knock down transcription factors at the protein levels, can hijack the ubiquitin-proteasome degradation system to initiate the intracellular ubiquitin-proteasome hydrolysis process to degrade proteins. In the past, the...

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Bibliografiske detaljer
Udgivet i:Transl Androl Urol
Main Authors: Chen, Xuanrong, Shen, Haishan, Shao, Yi, Ma, Qianwang, Niu, Yuanjie, Shang, Zhiqun
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7947434/
https://ncbi.nlm.nih.gov/pubmed/33718095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau-20-1357
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